GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9362426 | 1 | rs406900 | chr6:88085447 | C6orf164 | chr6:88032306-88109459:+ | -0.5 | -4.99 | 2.68E-6 | Depressive episodes in bipolar disorder |
| THYM | cis | rs2275426 | 1 | rs4073846 | chr1:46462881 | CCDC163P | chr1:45960581-45965646:- | 0.49 | 6 | 3.55E-8 | Body mass index |
| THYM | cis | rs9902453 | 1 | rs4074170 | chr17:28381141 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs9894429 | 1 | rs4074915 | chr17:79579230 | TSPAN10 | chr17:79609349-79615778:+ | -0.63 | -6.68 | 1.61E-9 | Eye color traits |
| THYM | cis | rs9894429 | 1 | rs4074916 | chr17:79579248 | TSPAN10 | chr17:79609349-79615778:+ | -0.63 | -6.68 | 1.61E-9 | Eye color traits |
| THYM | cis | rs9457247 | 1 | rs407515 | chr6:167407544 | RNASET2 | chr6:167343008-167412795:- | -0.46 | -7.49 | 3.6E-11 | Crohn's disease |
| THYM | cis | rs9902453 | 1 | rs4075623 | chr17:28386526 | EFCAB5 | chr17:28256874-28435469:+ | -0.31 | -4.25 | 5.04E-5 | Coffee consumption (cups per day) |
| THYM | cis | rs2275426 | 1 | rs4076006 | chr1:46438076 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs9457247 | 1 | rs408040 | chr6:167398903 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs408080 | chr6:167392522 | RNASET2 | chr6:167343008-167412795:- | -0.45 | -7.53 | 2.89E-11 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs408087 | chr6:167398952 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs408918 | chr6:167399282 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.78 | 8.78E-12 | Crohn's disease |
| THYM | cis | rs454422 | 1 | rs409035 | chr20:5943649 | MCM8 | chr20:5931298-5975829:+ | -0.22 | -4.5 | 1.96E-5 | HIV-1 viral setpoint |
| THYM | cis | rs9457247 | 1 | rs409356 | chr6:167405226 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs410128 | chr7:65603173 | CCT6P1 | chr7:65216092-65228661:+ | 0.6 | 4.91 | 3.81E-6 | Diabetic kidney disease |